Abstract:
To quantitative analysis and assess the blood perfusion characteristic of normal pancreas by Multisection dynamic CT.To investigate the perfusion parameters's change according to age, sex and difference locations of normal pancreas.30 cases with normal pancreas were examined for pancreatic perfusion and was divided into three sub-group according to age.The multisection dynamic CT perfusion series was performed for pancreatic perfusion on a multisection CT scanner(Siemens somatom Sensation 64), 120 kV, 100 mA.Contrast injection was done by using 50 mL nonionic contrast agent(300 mgI/mL), at a flow rate of 5 mL/s with a power injector, and 6 seconds delay.The data acquisition lasted for 30 seconds.These datas were processed on a SIEMENS workstation using PCT software package, and the mean
Fb,
Vb,
Ttp and
PS were measured and statistically analyzed in 30 cases with normal pancreas.The study showed that all perfusion parameters didn't influenced by age, sex and difference locations of pancreas(
P>0.05).The mean
Fb,
Vb,
Ttp and
PS in normal pancreas tissue were 133.55 ±25.70(mL/100mL/min), 193.78 ±27.01(mL/L), 142.41 ±13.95(0.1 s), 128.72 ±34.53(0.5 mL/100mL/min), respectively.The perfusion parameters in three sub-group according to age were not statistically significant(
P>0.05).The mean
Fb,
Vb,
Ttp and
PS in pancreas of male were 127.59 ±22.90(mL/100mL/min), 188.72 ±25.19(mL/L), 142.91 ±13.17(0.1 s), 133.30 ±42.86(0.5 mL/100mL/min), respectively and those parameters of female were 142.48 ±28.04(mL/100mL/min), 201.37 ±28.94(mL/L), 141.66 ±15.63(0.1 s), 121.85 ±14.80(0.5 mL/100mL/min), respectively.The perfusion parameters in male and female were not statistically significant(
P>0.05).The perfusion parameters in difference locations of pancreas were also not statistically significant(
P>0.05).MSCT perfusion imaging may reflect the features of normal pancreatic perfusion.All of perfusion parameters didn't influenced by age, sex and difference positions of pancreas.