Abstract: Objective: To compare the changes between Bio-Osten bone meal and Bio-Oss bone meal during the period of guided bone regeneration (GBR) in immediate implanting according to the data from the image by spiral CT scan. Methods: 15 patients who receive immediate implanting and GBR process in anterior teeth, were divided randomly into two groups including experimental group (Bio-Osten bone grafts, n = 7) and control group (Bio-Oss, n = 8). During dental implanting, the two groups were used Bio-Osten bone meal and Bio-Oss bone meal respectively and took spiral CT to scan the implanting area in 1 week, 3 months, 6 months after the procedures. According to the information from the image by CT scan, the volumes of bone meal in both groups were measured using Simplant analysis system .The remaining volume ratios were calculated in two groups in 3 months, 6 months after the procedures and analyzed statistically between two groups by the SPSS 16.0. Results: 3 months after operation, the absorption ratios were 41.51% ± 5.87%, 49.30% ± 5.78% in Bio-Osten group and Bio-Oss group, respectively. 6 months after operation, the absorption ratios were 58.02%±5.67%, 70.26%± 10.64%, respectively. There were significant difference between two groups (P ＜ 0.05) in both 3 months and 6 months. Conclusion: According to CT image, Bio-Osten and Bio-Oss have similar role in bone induction and similar biological absorption. In comparison, Bio-Osten was absorpted more slowly than Bio-Oss. Maybe Bio-Oss guided bone regeneration faster than Bio-Osten.