Abstract: Objective : To evaluate the clinical application of three dimension configuration in lung nodus. Material and Methods : Using helical computerized tomography (CT) scan with layer distance/disance between spires/configuration interval as 10mm/10mm/10mm and Fov 300mm-360mm。We made three dimension configuration on 53 cases of lung nodus which were found in routine CT scan and 100 controls in whom no nodus was found in routine CT scan. We defined-720 HU as lower limit of configuration (volume rendering) and compared the result with routing CT scan. Results : Among 53 positive cases, single nodus was found in 47 cases, with 21 in left lung and 26 in right lung. The diameter ranged from 0.5cm to 3.0cm. Rugged edge and vascular figure were clearer in helical than in routine scan. Double noduses were found in 2 cases and all proved to be benign later, with one as tuberculosis and the other as nonspecific infection. Multiple noduses of both lungs were found in 4, with 3 as carcinomatous metastasis and 1 as tuberculosis. Among 100 controls in whom no nodus was found in routine CT scan, a nodus (0.5cm) was found in 92 cases to have health examination and 2 was found in 8 cases with cancer (6 with esophagus cancer and 2 with lung cancer). Conclusions : Three dimension configuration of helical CT scan increased the sensitivity and showed clearer nodular edge feature. It contributes to reliable diagnosis of lung nodus and might be recommendable to clinical application.