Abstract: Objective: To investigate the MSCT imaging features of pulmonary sclerosing hemangioma(PSH) and comparison with the pathologic features, so that to improve the understanding and imaging diagnostic abilities of PSH. Methods: MSCT images of 39 cases with pathologically confirmed PSH were retrospectively reviewed.3 patients experienced only chest CT plain scan while the remained underwent both pre-and post-contrast CT scan. Results: This study comprised 6 male and 33 female with an average age of(46.9 ± 14.36) years. MSCT demonstrated all cases had solitary lesion, including 19 cases in the left lung and 20 in the right. 30 cases were peripheral and 9 were central. 32 cases demonstrated as subpleural lesions, 15 of which sticking to pleural with wide base; while 7 were non-subpleural. PSHs manifested as well-defined, round or ovoid nodules or masses, with a largest diameter ranged 5~57 mm. 11 cases presented slight lobulation. On pre-contrast CT, the density was homogeneous in 33 cases while heterogeneous in 6, with mean CT value of(34.0 ± 13.4)HU. Calcification was visible in 12 cases. After administration of contrast media, 30 lesions exhibited moderate or markedly enhancement, including 22 homogeneous and 14 heterogeneous. Hypodense necrotic area was presented in 4 lesions. The CT attenuation value in arterial phase was(77.0 ± 25.6)HU, and(91.0 ± 17.1)HU in venous phase during when gradual and continuous enhancement was found in 18 cases. Welt vessel sign(30 cases) and surrounding ground-glass opacity(4 cases) were also demonstrated. Conclusion: PSH MSCT findings of welt blood vessels sign、surrounded GGO sign, significant pulmonary artery sign, air crescent sign, tail sign has, which can help improve the preoperative diagnostic accuracy.