Abstract: Objective: To analyse the CT finding of solitary pulmonary tuberculoma. Methods: CT data of 26 cases proved of SPT by pathology were retrospectively analyzed. All patients were underwent chest CT scan.8 cases of those were performed by enhanced scan together. Results: Of 26 lesions, there were 13 lesions distributed in left lung and right lung respectively.18 lesions were distributed in the upper lung of apical posterior segment or below lung of dorsal lung segment.8 lesions were distributedin other segments. The long diameters of these lesions were between 3-54 mm. We got definite diagnosis of pulm-onary tuberculoma of 7 cases(27%), misdiagnosed 15 cases(58%) as per-ipheral lung cancer, and misdiagnosed 3 cases as inflammatory pseudot-umor, and misdiagnosed 1 case as other lesion. Conclusion: Solitary pul-monary tuberculoma could misdiagnose as lung cancer or other lesions. CT-guided percutaneous lung biopsy is an effective method for diagno-sis of pulmonary tuberculoma.