Abstract: Objective: To evaluate the diagnostic value of multislice CT enterography for gastrointestinal bleeding diseases. Methods: 16 patients with clinically suspected gastrointestinal bleeding diseases were all examined using multislice CT enterography after bowel preparation. The patients were initially performed with 0.62 mm slice thickness plain scans and a bolus-tracking software and then three phase enhanced scan using multi-modal reorganization such as multiplanar reconstruction, maximum intensity projection, and volume rendering. Results were compared with those from a reference standard(surgery or endoscopy) and clinical follow-up. Results: In 16 clinically suspected cases of gastrointestinal bleeding disorders, multislice CT enterography and final diagnosis findings were in agreement in 8 cases. Sites of hemorrhage depicted by multislice CT enterography were as follows: 3 cases of jejunal hemorrhage, 2 cases of ileal hemorrhage, 1 case of ileocecal hemorrhage, 1 case of ascending colon hemorrhage, 1 case of internal hemorrhoid. One of 8 patients with positive multislice CT enterography results had an active bleeding. The reason of the hemorrhagic lesions was diverticulitis in 1 cases(confirmed at endoscopy), gastrointestinal stromal tumor in 1 cases(confirmed at surgery), lymphoma in 1 cases(confirmed at surgery), internal hemorrhoid in 1 case. In one case, multislice CT enterography and final diagnosis results were both positive but were not in agreement on the bleeding source. In one case, both mulitislice CT enterography and final diagnosis findings were negative. The results of mulitislice CT enterography were negative in six of 16 patients with positive findings of final diagnosis. Conclusion: Mulitislice CT enterography with relative reconstruction techniques has high value for detecting the site of hemorrhage and detecting the cause of gastrointestinal bleeding.