ISSN 1004-4140
CN 11-3017/P

非心电门控低剂量平扫MDCT评价心外膜脂肪组织

Quantification of Epicardial Adipose Tissue in Non-ECG-gated Low-radiation-dose MDCT

  • 摘要: 目的:采用非心电门控低剂量平扫MDCT定量EAT容积并评价与冠脉CTA图像所测量EAT容积值的相关性和一致性。方法:对61例受检者行回顾性心电门控技术冠状动脉CTA和胸部低剂量肺癌筛查CT平扫。采用GE AW4.4工作站手动勾画心包线并计算两种扫描方式所测EAT容积。非门控低剂量平扫CT图像脂肪组织阈值设定范围为-195~45 Hu;冠脉CTA图像脂肪组织阈值设定范围分为5组,分别为-175~-25 Hu、-170~-20 Hu、-165~-15 Hu、-160~-10 Hu、-155~-5 Hu。结果:非门控低剂量平扫CT图像所测值与冠脉CTA图像所测值有很好的相关性(r分别为0.996、0.997、0.997、0.997、0.996)。当冠脉CTA图像脂肪组织阈值范围取值为-165~-15 Hu时,所测的EAT容积与非门控低剂量平扫CT图像所测值无统计学差异(P=0.125)。结论:低剂量非心电门控平扫CT图像能够进行EAT容积的评价,且与通常使用的冠脉CTA图像评价结果相比有较好的相关性和一致性。

     

    Abstract: Objective:To quantify the EAT volume in non-ECG-gated low-radiation-dose MDCT and assess the relationship of EAT volume in non-ECG-gated MDCT in comparison with ECG-gated Coronary CTA.Method:In all,61 patients were enrolled in this study and underwent retrospective ECG-gated coronary CTA and non-ECG-gated low-radiation-dose MDCT for lung cancer screening.The EAT volume was calculated through depicted the epicardium with AW4.4 workstation(GE).The threshold of EAT quantification in non-ECG-gated CT was -195~- 45 Hu.A total of five programs of the thresholds of EAT quantification in coronary CTA would be built(-175~- 25 Hu,-170~- 20 Hu,-165~-15 Hu,-160~-10 Hu,-155~- 5 Hu respectively).Result:The EAT volume quantification in non-ECG-gated MDCT had a significant relationship with the quantifications in ECG-gated Coronary CTA(r=0.996,r=0.997,r=0.997,r=0.997,r=0.996 respectively).When the threshold of EAT quantification in ECG-gated Coronary CTA was -165~-15 Hu,no significant difference was observed for EAT volume quantification with non-ECG-gated MDCT with respect to ECG-gated Coronary CTA(P=0.125).Conclusion:Non-ECG-gated low-radiation-dose MDCT allows quantifying EAT with almost the same consistency and correlation as using ECG-gated Coronary CTA.

     

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