Abstract: Objective: Study on intravenous urography (IVP) combined with multi-slice spiral CT (MSCT) examination in the value of urethral obstruction check. Materials and methods: Will clinical suspected diagnosis for ureteral disease patients first line IVP check, from IVP check in the elected hreteral obstruction patients 40 cases again line MSCT fiat sweep for research object, will original information pass to AW 4.2 workstation, respectively for more plane restructuring (MPR), and surfaces restructuring (CPR), and volume reproduce (VR) and maximum density projection (MIP); comparison simple IVP and the IVP + MSCT diagnosis results and surgery results in ureteral obstruction check in the of positioning, and qualitative accuracy. Results: IVP + MSCT diagnosed 38 cases, diagnosis rate was 95% (38/40); simple 1VP diagnosed 27 cases, diagnosis rate was 67.5% (27/40), with significant difference between them (P ＜ 0.01). Simple IVP and IVP+ MSCT in the diagnosis of ureteral obstruction has better consistency. Conclusion: IVP + MSCT scan on ureteral obstruction positioning, qualitative diagnosis more accurate and significantly reduced the radiation dose and the contrast dose, saving time and labor, and save the cost of examination