Abstract: Objective: To explore the value of DSCT in quantitative assessment of left ventricular function of coronary heart disease with T2DM.Methods: All of 152 CHD patients including 76 cases with T2DM and 76 cases without DM were performed angiographies by DSCT.Then the left ventricular function and characteristics of coronary artery were analyzed and compared between two groups.58 cases of them underwent cardiac DSCT and echocardiography examination within three days.Compared the correlations between DSCT and echocardiography in quantitative assessment of left ventricular functional parameters.Results: DSCT and echocardiography had good correlation for EF(r=0.702),ESV(r=0.874),SV(r=0.828) and EDV(r=0.898).There was no significant difference among the measurements between DSCT and echocardiography(P>0.05).The ESV and EDV measured by DSCT in the T2DM group were higher than that in non-DM group,while the EF was lower in the T2DM group.There was statistically significant between two groups(P<0.05).Calcification score had significant increase in T2DM group as compared with that in non-DM group.Three branch vessel lesion,severe stenosis and total occlusion of CHD with T2DM group have much more than that of CHD with non-DM group,while CHD with non-DM group have more one-vessel lesion and mild stenosis.Conclusion: DSCT is an accurate and feasible methods to assess the left ventricular function.The data obtained from one time coronary artery angiography can not only be used to evaluate left ventricular function but also to analysis the characteristics of coronary artery lesion.Compared with non-DM patients,the T2DM patients have more,extensive and severe coronary artery lesion and worse left ventricular function.