Abstract: Objective: To study features of diffuse panbrochiolitis(DPB) on high resolution computed tomography(HRCT).Methods: Retrospective analysis of radiographic and pathologic data of 5 patients with DPB was made.Results: 5 patients with DPB presented with centrolobular non fused node shadows being distributed diffusely on both lung fields.Typical chest HRCT scan showed “tree-in-bud” in 2 cases;the wall being thickened in small airway,tubular or ring shaped cap illary bronchiectasis in 3 cases;centrilobular emphysema in 3cases;paranasosinusitis in 5 cases.Conclusion: DPB have characteristic imaging features,which are the key to accurately diagnose this disease,particularly on HRCT.