Abstract: Objective: To explore the comparative value of CT plain scan,CT cerebral perfusion imaging(CTP),diffusion-weighted imaging(DWI)and MSCT angiography(CTA)in the acute ischemic cerebrovascular disease,and to find a reasonable procedure of imaging examination for acute ischemic cerebrovascular disease.Methods: Examinations of conventional CT,CT cerebral perfusion imaging,diffusion-weighted imaging and MSCT angiography were underwent in 30 cases with acute ischemic cerebrovascular disease.Results: In the 30 cases,plain CT showed the resulting ischemia and infarction in 12 cases.The sensitivity of DWI and CTP for diagnosing acute ischemic cerebrovascular disease were 73.3%,83.3%;The predictive value of positive cases of DWI and CTP were 95.7%,92.6%.Differences in sensitivity and the predictive value of positive cases were not statistically significant among DWI and CTP.CTA demonstrated the involved cerebral arteries for patients of acute ischemic cerebrovascular disease in 27 cases.Conclusion: Conventional CT is the first method of case selection in diagnose in clinic.CTP and DWI are both highly sensitive methods for detecting acute brain ischemia.CTA is helpful in finding the involved cerebral arteries.According to patients'clinical manifestation and economy condition,we cleverly choose these methods.