Abstract: Objective: To study the clinical significance of acute brain injury and brain midline basilar cistern dynamic observation of CT. Materials and methods: Right from May 2007 to July 2009 among 150 patients admitted with full information for basilar cistern and brain midline of the change in CT with acute head injury and to study the relationship between the prognosis of patients. Results: Narrowed by the basal cistern and extent of midline shift was divided into Ⅳ,this set of data shows the death rate in patients with traumatic brain injury type of the increased CT significantly improved,dynamic observations of the development of the disease with mortality rates significantly increased. Conclusion: Dynamic pool of acute brain injury and brain midline basal CT image changes,to predict prognosis and guide the rescue have important clinical significance.