Abstract: Objective: To analysis the CTA characteristics of myocardial bridge and the relationship with coronary artery atherosclerosis. Methods: 92 patients undergone CT angiography (CTA) were reviewed for this study and MIP, CPR, VR were performed and study. Further, analyzed the relationship between myocardial bridge and atherosclerosis in LAD. Results: 23 patients with myocardial bridge were found in all 92 patients (25 %), 18 in LAD (78.2%). The difference of atherosclerosis prevalence between the proximal coronary artery with myocardial bridge group and no myocardial bridge group showed a statistical significant (P<0.05). Conclusion: MSCT coronary angiography is an accurate and non-invasive method in diagnosing myocardial bridge. Myocardial bridge is a important reason of coronary artery atherosclerosis.