ISSN 1004-4140
CN 11-3017/P

喉癌CT分型和CD44V6表达的意义

Significince of Pattern and Expressions of CD44V6 in Larygeal Carcinomas

  • 摘要: 目的 探讨喉癌的CT分型和转移相关因子CD44V6表达的意义。方法 对39例喉鳞癌行术前常规CT检查,其术后标本进行CD44V6的表达检测,与术前CT片作对照分析。结果 39例喉鳞癌CT检查:声门型24例,声门上型14例,跨声门型1例,声门下型0例;T1-2级22例,T3-4级17例;淋巴结转移组13例,非转移组26例,CD44V6总的阳性表达率为61.5%,对各组均采用秩次检验分析,CD44V6在喉癌的CT的T分级和淋巴结分组中存在显著性差异(P<0.01)。而部位分区无明显差异。结论 喉癌的CT分型中的T分级、淋巴结分组与CD44V6的阳性表达密切相关。

     

    Abstract: Objective To investigate the significince of CT pattern and expressions of metastasis factors CD44V6 in larygeal carcinoma. Methods CT senning and expressions of CD44V6 were done in 39 patients with larygeal carcinoma. Results CT pattern: glotlis calegory (24/39)、 over glotlis category (14/39) and cross glotlis culegory (1/39), T1-2(22/39)、 T3-4(17/39),lymph node metastasis (13/39) no lymph node metastasis (24/39). Positive immunoseactivity of CD44V6 were 61.5% in 39 cases. Expressions of CD44V6 were distinel deffesence in T classification and lymph node metastasis (p<0.01), and nl deffesence in position. With adet testing analycine. Conclusions CD44V6 Positine expressions were closely associated with T classification and lymph node metastasis in larygeal carcinoma.

     

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