Abstract: Objective: The purpose of this study was to explore the application of multislice CT perfusion imaging in uterus and uterine leiomyoma.Methods: Routine pelvic CT was performed in 17 cases and then CT perfusion imaging was made at selecting slice.The contrast material was bolus injected through forearm superficial vein,while 4 slices of dynamic scan was performed for 40 seconds.The dynamic images were processed by Perfusion CT software package,and then the Blood Flow,Blood Volume and Time to Peak of the uterine leiomyoma and the normal uterine tissue(around the tumor) were measured and documented respectively.Results: All cases of multislice perfusion imaging were successfully performed.A significant difference in Blood Flow between uterine leiomyoma and the normal uterine tissue(around the tumor) was showed.The Blood Flow,Blood Volume and Time To Peak of the uterine leiomyoma were(54.87±19.09)ml.100g^-1.min^-1,(12.41±4.07)% and(18.61±5.31)s.The Blood Flow,Blood Volume and Time To Peak of the normal uterine tissue(around the tumor) were(32.82±17.68)ml.100g^-1.min^-1,(8.78±6.25)% and(20.64±5.71)s.Conclusion: Multislice CT perfusion imaging provided a new imaging method for measuring the uterine hemadynamic.