Abstract: The Liangzi Lake depression is located in the eastern part of the urban agglomeration in Wuhan at the junction of Wuhan, Huangshi, Ezhou, and Xianning, and controls the formation of surrounding lakes. It was mainly formed by the combined influence of the Macheng–Tuanfeng fault and southeastern Hubei tilted movement. In this study, three shallow seismic reflection profiles were arranged in the north–central–south direction of the Liangzihu Lake to obtain the shallow geological structure of the Liangzihu fault depression and analyze the underground morphology of the southern section of the Macheng-Tuanfeng fault. The analyzed results show that the Liangzihu depression is a large-scale early cretaceous synclinal structure with the northern edge of the fault depression located along the line joining the Gedian and Linjiang Township, and the southern edge located along the line joining the Shanpo Township and the Town of Jinniu; the Macheng-Tuanfeng fault passes through the west side of the Liangzi Lake, starting from Tuanfeng Town and gradually disappearing in the Town of Jinniu. The research results provide a strong basis for the study of the Liangzihu fault depression, construction planning, and earthquake risk assessment of the urban agglomeration in Wuhan, and have considerable scientific and social importance.