ISSN 1004-4140
CN 11-3017/P

心肌细胞外容积在TAVI术前评估中的应用价值

Application Value of Myocardial Extracellular Volume in Preoperative Assessment of TAVI

  • 摘要: 目的:探究双能CT测量的心肌细胞外容积(ECV)在经导管主动脉瓣置入(TAVI)术前风险分层评估中的应用价值。方法:前瞻性纳入2023年6月至2024年6月行TAVI术前CT评估的患者71例。患者均接受了双能CT延迟增强扫描用来计算ECV,根据ECV中位数分为高ECV组和低ECV组。观察各组患者TAVI手术及术后早期恢复情况。结果:测得71例患者的中位ECV为33.92±6.37%,并观察到49例患者最终在本院接受了TAVI手术,高ECV组26例,低ECV组23例。术后高ECV组住院天数、ICU停留天数及心血管不良事件的发生率大于低ECV组,差异具有统计学意义。ECV与术后住院天数呈现正相关(r=0.446, P=0.002),多因素Logistic回归分析显示ECV是患者术后短期发生心血管不良事件的独立危险因素(OR=1.399, P=0.037)。结论:基于双能CT的心脏ECV具有主动脉瓣病变患者TAVI术前风险分层的潜力。

     

    Abstract: Objective: To explore the value of myocardial extracellular volume measured using dual-energy computed tomography (CT) in preoperative risk stratification for transcatheter aortic valve implantation (TAVI). Methods: We prospectively included 71 patients who underwent CT assessment before TAVI between June 2023 and June 2024, all of whom underwent dual-energy CT-delayed enhancement scans to calculate the ECV. Based on the median ECV, the patients were divided into high-ECV and low-ECV groups. The aim was to observe TAVI surgical outcomes and early postoperative recovery among the two patient groups. Results: The median ECV of the 71 patients was 33.92 ± 6.37%. Of these, 49 patients ultimately underwent TAVI surgery at our hospital, with 26 patients in the high-ECV group and 23 patients in the low-ECV group. The postoperative hospital stay, intensive care unit (ICU) stay, and incidence of cardiovascular adverse events were significantly greater in the high-ECV group than in the low-ECV group. Correlation analysis showed a positive correlation between ECV and the length of postoperative hospital stay (r=0.446, P=0.002). Multifactorial logistic regression analysis showed that ECV was an independent risk factor for short-term postoperative adverse cardiovascular events (OR=1.399, P=0.037). Conclusion: Cardiac ECV based on dual-energy CT has potential for preoperative risk stratification in patients with aortic valve disease undergoing TAVI.

     

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