ISSN 1004-4140
CN 11-3017/P
王龙停，柳峰，王凯亮，等. 不同体质量指数双低剂量冠状动脉CTA的应用研究[J]. CT理论与应用研究（中英文），xxxx，x(x): 1-6. DOI: 10.15953/j.ctta.2024.115.
引用本文: 王龙停，柳峰，王凯亮，等. 不同体质量指数双低剂量冠状动脉CTA的应用研究[J]. CT理论与应用研究（中英文），xxxx，x(x): 1-6. DOI: 10.15953/j.ctta.2024.115.
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WANG L T, LIU F, WANG K L, et al. Application Study of Double Low Dose in Coronary Computed Tomography Angiography with Different Body Mass Indices[J]. CT Theory and Applications, xxxx, x(x): 1-6. DOI: 10.15953/j.ctta.2024.115. (in Chinese).
Citation: WANG L T, LIU F, WANG K L, et al. Application Study of Double Low Dose in Coronary Computed Tomography Angiography with Different Body Mass Indices[J]. CT Theory and Applications, xxxx, x(x): 1-6. DOI: 10.15953/j.ctta.2024.115. (in Chinese).
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不同体质量指数双低剂量冠状动脉CTA的应用研究

Application Study of Double Low Dose in Coronary Computed Tomography Angiography with Different Body Mass Indices

    摘要
  • 摘要: 目的：探讨不同体质量指数（BMI）患者低管电压低剂量对比剂在64排冠状动脉CTA（CCTA）的应用价值。方法：选择160例临床疑诊冠心病并行CCTA检查的患者为研究对象，按照BMI分为A组（18.5 <BMI< 24）和B组（24 ≤ BMI< 28），各80例，每组随机分为对照组（A1/B1组）和试验组（A2/B2组），各40例。对照组均采用120 kV管电压扫描，A1、B1两组分别采用60 mL对比剂+40 mL生理盐水、80 mL对比剂+20 mL生理盐水注射。试验组均采用双低剂量，即A2组80 kV管电压，40 mL对比剂+60 mL生理盐水，B2组100 kV管电压，60 mL对比剂+40 mL生理盐水，其余扫描参数均相同。扫描结束后重建图像，统计数据，比较对照组与试验组图像质量、辐射剂量、碘摄入量的差异。结果：A1和A2组图像合格率、优良率、SNR及CNR均无统计学差异（P >0.05），A2组主动脉CT值、图像噪声高于A1组（P <0.05）。B2组图像合格率、优良率、主动脉CT值、SNR及CNR均高于B1组（P <0.05），图像噪声与B1组无差别（P >0.05）。A2组、B2组CTDIvol、DLP、ED分别低于A1组、B1组（P <0.05）。ED比较，A2组较A1组减少68.3％，B2组较B1组减少41.6％。A2组、B2组碘摄入量分别减少33.3％、25％。结论：不同BMI患者采用低管电压低剂量对比剂行64排CCTA检查既能保证图像质量，又能明显降低辐射剂量并减少碘摄入量。

     

    Abstract: Objective: This study aimed to explore the applicative value of low tube voltage and low-dose contrast agents in coronary computed tomography angiography (CCTA) of 64 rows CT with different body mass indices (BMI). Methods: The participants were 160 patients with clinically suspected coronary heart disease who underwent CCTA examination and divided into groups A (18.5 < BMI < 24) and B (24 ≤ BMI < 28), with 80 cases in each group. Each group was randomly divided into the control ( A1/B1) and experimental groups ( A2/B2) with 40 patients in each group. The control group was scanned with 120 kV tube voltage, whereas groups A1 and B1 were injected with 60mL contrast agent + 40mL physiological saline and 80mL contrast agent + 20mL physiological saline, respectively. All experimental groups adopted a double low-dose method, with group A2 receiving 80 kV tube voltage, 40mL contrast agent + 60mL physiological saline, and group B2 receiving 100 kV tube voltage, 60mL contrast agent + 40mL physiological saline. All other scanning parameters were the same. After scanning, the images were reconstructed, data were collected, and differences in image quality, radiation dose, and iodine intake were compared between the control and experimental groups. Results: Image qualification rate, excellent rate, SNR, and CNR between groups A1 and A2 had no statistically significant difference (P >0.05). However, group A2 had higher aortic CT values and image noise than group A1 (P <0.05). The image qualification rate, excellent rate, aortic CT value, SNR, and CNR in group B2 were higher than in group B1 (P <0.05), and there was no difference in image noise between group B1 (P >0.05). The CTDIvol, DLP, and ED of groups A2 and B2 were lower than those of groups A1 and B1 (P <0.05). Compared with group A1, group A2 showed a 68.3% decrease in ED, whereas group B2 showed a 41.6% decrease compared to group B1. The iodine intake of groups A2 and B2 decreased by 33.3% and 25%, respectively. Conclusion: Using low tube voltage and low dose contrast agent in CCTA with different BMI not only ensure image quality, but also significantly reduce radiation dose and iodine intake.

     

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