Abstract: As an important indicator to describe reservoir characteristics, reservoir modeling and fluid model, the accurate estimation of reservoir physical parameters can provide a powerful reference for reservoir prediction, but the traditional inversion method of reservoir physical parameters can not give consideration to inversion accuracy and spatial continuity. To solve the above problems, this paper introduced seismic attributes as input of deep learning algorithm. Aiming at the information redundancy among seismic attributes, random forest-recursive elimination method was used to reduce the seismic attributes, thus a prediction method of reservoir physical property parameters based on seismic attribute reduction was finally established. The actual data test results showed that the prediction results of reservoir physical parameters by deep learning based on seismic attribute reduction presented good accuracy and lateral resolution, which confirmed the effectiveness of the proposed method.