Abstract: Objective: To explore the application of deep learning image reconstruction (DLIR) algorithm in upper abdominal CT imaging by analyzing the image quality of adaptive statistical iterative reconstruction (ASIR) algorithm and DLIR. Methods: Retrospectively included 75 patients’ upper abdominal CT plain scan images, using adaptive statistical iterative reconstruction algorithm ASIR (30%, 50%, 70%, 90%) and deep learning reconstruction algorithm (DL-L, DL-M, DL-H) to reconstruct images, a total of 7 groups. Measured the CT and SD values of the liver, pancreas, and erector spinae , and calculated the signal to noise ratio (SNR) and contrast to noise ratio (CNR). Objective indicators were evaluated by one-way ANOVA. Two radiologists scored the image quality and noise, and compared them with Friedman <i<M</i< test. Results: (1) The SD value, SNR, and liver CNR of the seven reconstructed images had statistically significant differences. (2) The difference in CT value, SD value, SNR value and CNR value at each ROI between DL-L and ASIR 50%, DL-M and ASIR 70%, DL-H and ASIR 90% was small. (3) The SNR value of the three DLIR algorithms increased as the level increased, and the difference was statistically significant; and the SNR value of the DL-H algorithm was higher than ASIR 30% and ASIR 50%, and the SD value was lower than the other five reconstruction algorithms except for the ASIR 90%. (4) The difference in the subjective scores of the seven groups of images was statistically significant. The algorithm DL-H had the best image quality and the lowest noise, DL-M, ASIR 90%, DL-L, ASIR 70%, ASIR 50%, ASIR 30% image noise in sequence increased. Conclusion: The DLIR algorithm can reduce the image noise of the upper abdomen and improve the image quality. As the level increased, the image noise decreased, the quality improved, and the signal-to-noise ratio increased.