Abstract: Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease that has erupted on all continents around the world. Knowledge of the clinical and imaging aspects of COVID-19 is the key to effective prevention, control, diagnosis and treatment of this infectious disease. Chest CT examination, as an important auxiliary inspection method for COVID-19, plays a key role in the epidemic. This article summarizes the clinical and CT manifestations of COVID-19 based on related research on nucleic acid and clinical diagnosis of COVID-19 patients in China.