Abstract: Novel coronavirus pneumonia has been outbroken in many countries around the world. How to improve the early screening rate has become the focus of epidemic prevention and control. Computed tomography (CT) has played an important role in the early screening and disease monitoring of novel coronavirus pneumonia in China. Therefore, it is particularly important to improve the accuracy of imaging doctors in the diagnosis of pneumonia. The purpose of this paper is to review the value, diagnosis and differential diagnosis points of CT in screening of novel coronavirus pneumonia, and to compare the CT manifestations of novel coronavirus pneumonia with other viral pneumonia or bacterial pneumonia, in order to make CT play a better role in the prevention of epidemic situation in the future, through assisting to the early detection and isolation of patients.