Abstract: To investigate the imaging characteristics of diabetic Charcot foot and provide clinical basis for diagnosis. Materials and methods:the imaging findings of 16 cases of diabetic Charcot treated by surgery in our hospital between January 2016 and September 2019 were retrospectively analyzed. Results:There were local ulceration infection and effusion in 16 cases. X-ray manifestations described osteoporosis in 13 patients, bone destruction in 10 patients, bone hyperplasia in 6 patients, joint deformity in 12 patients (including foot joints), bone fracture in 1 patient, change in articular surface/joint space in 4 patients, and soft tissue swelling in 11 patients respectively. CT and MRI showed disorganized foot structure, abnormal bone morphology and poor joint alignment. MRI showed edema of bone marrow and soft tissue and abnormal fluid signal. CTA showed arteriovenous fistula of the lower leg. Conclusion:the imaging diagnosis of diabetic Charcot foot is mainly bone destruction and plasticity, and the early imaging manifestations are difficult to differentiate from other diseases, which should be based on clinical patients with diabetic peripheral neuropathy