A Comparative Study of Non-contrast Cardiac CT and Coronary CT Angiography in Quantitative Analysis of Epicardial Fat Volume
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摘要: 目的:对比研究基于心电门控的心脏CT平扫(NCT)与冠状动脉CTA定量评价冠心病患者心外膜脂肪体积(EFV)的一致性。方法:回顾性分析临床诊断冠心病同期行心脏CT平扫和冠状动脉CTA检查患者40例。心外膜边界由2位具有丰富心血管CT临床工作经验的医师(观察者1和2)采用GE AW4.7工作站自动软件自动勾勒心外膜轮廓,EFV结果由软件自动计算生成。采用线性回归分析、Bland-Altman分析法及组内相关系数(ICC)评价两观察者间的一致性。结果:NCT和冠状动脉CTA测得EFV分别为(99.43±43.78)cm3和(93.66±48.49)cm3,两者差异无明显统计学意义(P>0.05)。观察者1在NCT和CTA的重复系数(CR)误差分别为10.01cm3和7.83cm3;观察者2在NCT和CTA的CR误差分别为11.05cm3和7.58cm3。NCT的CR为8.05cm3;CTA的CR为7.13cm3。各组ICC均大于0.96。结论:基于心电门控的心脏CT平扫和冠状动脉CTA均可用于EFV的评估。Abstract: Objective: To compare non-contrast cardiac CT (NCT) and coronary CT angiography (coronary CTA) for quantitative analysis of epicardial fat volume (EFV) in coronary artery disease cohort. Method: Forty patients underwent retrospective NCT and coronary CTA with ECG-gated. Epicardial boundaries were traced by 2 experienced radiologists (operator 1 and operators 2). EFV was calculated by Autocontour software (AW4.7 workstation, GE). Linear Regression, Bland-Altman method, Coefficient of Repeatability (CR) and Intra Class Correlation (ICC) were computed to analyze the inter-observer variability. Result: There was no significant difference (P>0.05) between NCT (99.43±43.78cm3) and coronary CTA (93.66±48.49cm3) in mean EFV values. For operator 1, CR errors were 10.01cm3 (NCT) and 7.83cm3 (coronary CTA), respectively. For operator 2, CR errors were 11.05 cm3 (NCT) and 7.58cm3(coronary CTA), respectively. ICC values >0.96 were obtained in all cases. CR values were 8.05 cm3 for NCT and 7.13cm3 for CTA. Conclusion: Both NCT and coronary CTA can be used to computer-assist measurements of EFV with ECG-gated.
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Keywords:
- cardiovascular disease /
- epicardial adipose tissue /
- tomography /
- X-ray computed
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期刊类型引用(4)
1. 张益民,郑一兵. 心脏CT平扫与CT血管造影定量分析对心外膜脂肪体积的测定效果比较. 实用临床医药杂志. 2022(03): 21-24 . 百度学术
2. 梁健华,林永开,吴洁瑶,邓立维,杨春阳,李远章. 低剂量心脏平扫与冠脉CT血管造影在测量心外膜脂肪体积方面具有等效性. 分子影像学杂志. 2022(02): 189-193 . 百度学术
3. 姜育,张洁,陈群,李亚. 心外膜脂肪组织厚度对2型糖尿病合并冠心病患者血管事件发生的预测价值. 陕西医学杂志. 2021(05): 542-545+554 . 百度学术
4. 董相宇,方挺松,王文会,袁健祥,冯有丽,梁振华,杨延斌. 单位体表面积心外膜脂肪容积与房颤的相关性研究. CT理论与应用研究. 2020(06): 702-710 . 本站查看
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