Abstract: Objective: Intra-abdominal aggressive fibromatosis and stromal tumors are easily confused in diagnosis, so comparative analysis the CT findings of both, to summary their key points of differential diagnosis. Methods: The difference of both in sites, cystic degeneration or necrosis, enhancement phase and enhancement degree were significant (P=0.01), it has high value for differential diagnosis, among them, enhancement phase and enhancement degree have important value. There was significant difference between both in the size, morphology and boundary of the lesion, as well as blood vessels, bleeding, gas and calcification in lesions, it has certain value for differential diagnosis. Conclusion: If the lesion is located outside the gastrointestinal, without cystic degeneration or necrosis, enhanced scan showed slight enhancement, and time-density curve showed slowly ascending linear type, we should consider intra-abdominal aggressive fibromatosis. If the lesion is located in the gastrointestinal wall, with cystic degeneration or necrosis, enhanced scan showed moderate to marked enhancement, and time-density curve showed parabola type, we should consider stromal tumors.