Evaluation of Alveolar Bone Changes in Chronic Periodontitis Before and After Sequence of Periodontal Treatment by CBCT
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摘要: 目的：应用锥形束CT（CBCT）评价重度慢性牙周炎基础治疗对比基础治疗合并翻瓣手术治疗的疗效。方法：选取近3年初诊的重度慢性牙周炎患者，纳入仅进行牙周基础治疗的20例和进行基础治疗合并翻瓣手术治疗20例为研究对象，对治疗前后上颌前磨牙进行牙周探诊深度（PD）、附着丧失水平（CAL）的临床效果观察，并拍摄CBCT，利用CBCT随机软件测量牙槽骨骨密度（ABD）。对两组间治疗前后疗效指标的变化值进行协方差分析。结果：共40名研究对象合计治疗评估145颗患牙，其中基础治疗组72颗，基础治疗合并翻瓣手术组73颗。基础治疗合并翻瓣手术治疗组治疗前后PD（-1.25 vs.-2.00，P<0.001）的降低，牙槽骨密度ABD（0.027vs.0.059，P<0.001）的增高较单纯基础治疗组更加明显，两组在CAL变化差值表现不明显。结论：基础治疗合并翻瓣手术治疗比单纯基础治疗在临床指数PD以及牙槽骨密度等方面疗效变化更好。Abstract: Objective: To compare change in PD(periodontal probing), CAL(clinical attachment loss) and ABD(alveolar bone density) between the initial therapy and initial therapy flap surgery groups from baseline to end of follow-up(6 months). Methods: Patients with severe chronic periodontitis were observed in the initial therapy group(20) and the initial therapy flap surgery group(20). Totally 40 patients were followed up for 6 months after both treatment.Outcomes for PD, CAL and ABD for each tooth were collected at two time points(baseline and 6 months after treatment). Descriptive analysis was used to summarize the demographic characteristics. A mixed-model ANCOVA will be conducted, controlling for covariates of baseline outcome value, age, sex and alcohol intake, to evaluate the treatment difference between the initial therapy group and initial therapy flap surgery group in change from baseline of the outcomes. Results: A total of 145 teeth(72 in the initial therapy group, and 73 in the initial therapy flap & surgery group) were evaluated. Teeth that received the initial therapy flap surgery group performed better in change from baseline of PD than teeth that received the initial therapy group(-1.25 vs.-2.00, P<0.001). There is no statistical significance treatment difference in change from baseline of CAL between two groups. Teeth that received the initial therapy flap surgery group performed better in change from baseline of BMD than teeth that received the initial therapy group(0.027 vs. 0.059, P<0.001). Conclusion: There may be substantial benefits for patients who received the initial therapy flap surgery group than the initial therapy group only. CBCT could be used in evaluation of alveolar bone changes in the Sequence of periodontal treatment of chronic periodontitis
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期刊类型引用(4)
1. 张昊. 冠状动脉CTA在冠脉支架评估中的应用进展. 中国医疗器械信息. 2020(03): 35-36 . 
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3. 刘小红，李丰章，李琪. 宝石能谱CT扫描在肺肿瘤诊断中的应用价值. 中国当代医药. 2019(30): 113-115 . 百度学术
4. 沈松鹤，赵森，朱鸷翔，周青，赵锡利，王志学. 宝石能谱CT心脏高清与非高清扫描方式对冠状动脉支架显示清晰度的影响. 医学影像学杂志. 2018(09): 1452-1456 . 百度学术
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