Abstract:
Objective: To investigate the correlations of the dynamic contrast enhancement MRI (DCE-MRI) and glucose metabolism determined by the maximum standardized uptake value (SUV
max) at
18F-FDG PET/CT in small peripheral cell lung cancer. Methods:
18F-FDG PET/CT and DCE-MRI wereperformed in 27 consecutive patients with histologically verifiedsmall peripherallung cancer (maximal diameter ≤ 3 cm). The quantitative MR pharmaeokineticparameters including
Ktrans,
Kep,
Ve and SUV
max were measured. Pearson's correlations were conducted between the three MR parameters and SUV
max.Results: Positive correlations were found between
Ktrans and SUV max,
Kep and SUV
max (
P < 0.05). No significant correlation was found for thecomparison of
Ve and SUV max (
P>0.05). Conclusions: Positive correlationswere found between
Ktrans and SUV
max,
Kep and SUV
max. Combination of three parameters can reflect the malignant feature of lung cancer.