摘要:
目的:探讨双源双能量CT(DECT)彩色编码技术对痛风患者不同临床时期尿酸盐结晶与血尿酸的关系,进而评估双能CT成像在痛风筛查中的应用价值。方法:回顾性分析120例高尿酸血症或痛风患者的双能CT成像特点及临床资料,根据临床分期分为两组,男92例,女28例;对照组为非痛风患者30例,男26例,女4例。所有患者手、足均行DECT非增强扫描,薄层重组后将原始数据传至MMWP工作站选择Dual Energy GOUT软件,进行影像后处理,比较痛风患者两期尿酸盐沉积的差异与尿酸值相关性,以及DECT检测尿酸盐沉积部位与临床评估的差异。采用t检验、χ2检验、Fisher精确概率进行统计学分析。结果:三组性别及年龄比较,差异无统计学意义(P年龄=0.236,P性别=0.613,P>0.005)。高尿酸组尿酸盐沉积量明显高于尿酸正常组,两组有显著统计学意义(P=0.000,P<0.001);痛风组检出率与对照组相比,差异有显著统计学意义(P=0.000,P<0.001)。结论:DECT成像技术对尿酸盐结晶沉积有很好的显示能力,对高尿酸血症、痛风早期、疑似痛风患者均有较高的检出率,可作为痛风筛选的常规检查项目,具有较高的临床应用价值。
Abstract:
Objective: To evaluate dual source CT dual energy(DECT) color coding technology in patients with gout urate crystals and different clinical period the relationship, between blood uric acid and further evaluation of dual-energy CT imaging in the gout screening application value. Methods: Retrospective analysis 120 cases of patients with Hyperuricemia or gout dual-energy CT imaging characteristics and clinical data, According to the clinical stage can be divided into two groups of 92 cases of male and female 28 cases; 30 cases of control group for the pseudogout patients, male 26 cases, female 4 cases, All cases of hand, footline DECT non enhanced scan, thin layer after restructuring would transmit the original data to choose MMWP workstation Dual Energy GOUT software, image post-processing, comparing the difference between the patients with GOUT two uric acid salt deposition and uric acid value relevance, and DECT detection urate deposition area and the difference of clinical evaluation. Using t test and chi-square test, Fisher exact probability statistical analysis. Results: Three groups of gender and age, there was no statistically significant difference(Page= 0.236, Pgender= 0.613, P > 0.005). Urate deposition quantity high uric acid group was obviously higher than that of uric acid in the normal group, two groups have significant statistical significance(P = 0.00013, P < 0.001); Gout group detection rate compared with the control group, with significant difference statistically significant(P = 0.00015, P < 0.001). Conclusion: DECT imaging of urate crystals, the deposition has a good ability of hyperuricemia, early gout patients and suspected gout have a higher detection rate, can be used as a routine examination gout screening project, has high clinical value.
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