Abstract: Objective: To evaluate dual source CT dual energy(DECT) color coding technology in patients with gout urate crystals and different clinical period the relationship, between blood uric acid and further evaluation of dual-energy CT imaging in the gout screening application value. Methods: Retrospective analysis 120 cases of patients with Hyperuricemia or gout dual-energy CT imaging characteristics and clinical data, According to the clinical stage can be divided into two groups of 92 cases of male and female 28 cases; 30 cases of control group for the pseudogout patients, male 26 cases, female 4 cases, All cases of hand, footline DECT non enhanced scan, thin layer after restructuring would transmit the original data to choose MMWP workstation Dual Energy GOUT software, image post-processing, comparing the difference between the patients with GOUT two uric acid salt deposition and uric acid value relevance, and DECT detection urate deposition area and the difference of clinical evaluation. Using t test and chi-square test, Fisher exact probability statistical analysis. Results: Three groups of gender and age, there was no statistically significant difference(P_age= 0.236, P_gender= 0.613, P > 0.005). Urate deposition quantity high uric acid group was obviously higher than that of uric acid in the normal group, two groups have significant statistical significance(P = 0.00013, P < 0.001); Gout group detection rate compared with the control group, with significant difference statistically significant(P = 0.00015, P < 0.001). Conclusion: DECT imaging of urate crystals, the deposition has a good ability of hyperuricemia, early gout patients and suspected gout have a higher detection rate, can be used as a routine examination gout screening project, has high clinical value.