摘要:
目的:研究256层螺旋CT机头颈部血管成像(CTA)检查对原发性蛛网膜下腔出血(SAH)患者的诊断作用以及血清S-100B蛋白检测对SAH患者脑损害程度及脑血管痉挛的评价作用。方法:选取2013年4月至2014年3月期间我院收治的SAH患者共77例,根据格拉斯哥昏迷(GCS)评分和Hunt-Hess分级分成不同组别,对其进行256层螺旋CT机头部CTA检查及血清S-100B蛋白水平的检测。结果:在77例SAH患者中,经CT机头部CTA检查共有59处动脉瘤。GCS评分3~8分患者入院后1天、7天S-100B蛋白水平分别为(1.94±0.31)μg/L、(1.93±0.28)μg/L明显高于GCS评分9~12分患者入院后1天、7天S-100B蛋白水平(1.13±0.21)μg/L,(1.09±0.19)μg/L和GCS评分13~15分患者入院后1天、7天S-100B蛋白水平(0.54±0.09)μg/L,(0.52±0.06)μg/L,差异具有统计学意义(P<0.05)。Hunt-HessⅠⅡ级患者入院后1天、7天S-100B蛋白水平分别为(0.68±0.12)μg/L和(0.64±0.11)μg/L明显低于Hunt-HessⅢ级患者入院后1天、7天S-100B蛋白水平(1.15±0.18)μg/L,(0.98±0.12)μg/L和Hunt-HessⅣ级患者入院后1天、7天S-100B蛋白水平(2.08±0.25)μg/L,(1.99±0.23)μg/L,差异具有统计学意义(P<0.05)。结论:256层螺旋CT机头颈部CTA检查可对SAH患者周边血管三维结构予以有效反应,对SAH患者行S-100B蛋白水平检测,能有效对SAH患者脑损害程度及血管痉挛做出评价。
Abstract:
Objective: To study the diagnostic effect of SAH(CT) in the diagnosis of primary subarachnoid hemorrhage(CTA) and to evaluate the effect of serum S-100 protein on brain damage and cerebral vasospasm in SAH patients. Methods: patients with CTA from 2013 April 2014 march in our hospital, according to Glasgow Coma Scale(GCS) coma score and hunt Hess grade divided into different groups, they were detected by 256 slice spiral CT head CTA examination and serum S-100 B protein levels. Results: In 77 patients with SAH by CT sports a CTA examination 59 aneurysm. GCS score 3~8 points of patients admitted to hospital after 1 d, 7 d S-100 B protein levels were(1.94 ±0.31) μg/L respectively,(1.93 ±0.28) μg/L was significantly higher than patients with GCS score 9~12 points 1d, d after admission S-100 B protein levels(1.13 ±0.21) of μg/L,(1.09 ±0.19) μg/L and GCS score 13~15 points, 1 d, 7 d after admission in patients with S-100 B protein levels(0.54 ±0.09) of μg/L, μg/L(0.52 ±0.06), statistically significant difference(P<0.05). Hunt and Hess grade III patients admitted to hospital after 1 d, 7 d S-100 B protein levels were(0.68 ±0.12) μg/L,(0.64 ±0.11) of μg/L significantly lower than Hunt-Hess level III patients admitted to hospital after 1 d, 7 d S~100B protein levels(1.15 ±0.18) μg/L,(0.98 ±0.12) μg/L and Hunt-Hess level IV patients admitted to hospital after 1 d, 7 d S~100B protein levels(2.08 ±0.25) of μg/L,(1.99 ±0.23) μg/L, statistically significant difference(P<0.05). Conclusion: 256 slice spiral CT head and neck CTA scan can be effective response to the peripheral vascular three-dimensional structure of patients with SAH, the SAH patients with S-100 B protein level detection, can effectively evaluate the degree of brain damage and vascular spasm in SAH patients.
百度学术
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