ISSN 1004-4140
CN 11-3017/P
ZENG Ni, HE Jianhua, ZENG Jian, DUAN Xuqiong, XU Xiaomei, QIAO Jie. The First Clinical and CT Value Analysis of COVID-19[J]. CT Theory and Applications, 2020, 29(4): 416-423. DOI: 10.15953/j.1004-4140.2020.29.04.04
Citation: ZENG Ni, HE Jianhua, ZENG Jian, DUAN Xuqiong, XU Xiaomei, QIAO Jie. The First Clinical and CT Value Analysis of COVID-19[J]. CT Theory and Applications, 2020, 29(4): 416-423. DOI: 10.15953/j.1004-4140.2020.29.04.04

The First Clinical and CT Value Analysis of COVID-19

  • Objective:To analyze the value in the first clinical and chest CT features of Corona Virus Disease 2019(COVID-19). Methods:The first clinical symptoms、general inflammatory indicators and chest CT features of 90 patients with clinically diagnosed COVID-19 were retrospectively analyzed, which included 13 cases of severe/critical type and 77 cases of light/ordinary type. The results were analyzed and compared by two experienced radiologists. Results:Compared with the light/ordinary COVID-19 patients, the most important clinical characteristics of the severe/critical type were older age, general inflammatory indicators increased, and chest CT showed higher pulmonary inflammatory index(PII). The receiver operating characteristic curve(ROC) showed that the sensitivity of C-reactive protein(CRP) and PII to distinguish between severe/critical COVID-19 and light/ordinary COVID-19 was respectively 69.2% and 69.2%; The specificity was 83.1% and 87.0%, respectively; The Area Under Curve(AUC) were 0.77595% CI(0.649, 0.901); P=0.002 and 0.77095% CI(0.621, 0.920); P=0.002, respectively. The AUC of their association was 0.78595% CI(0.644, 0.927); P=0.001. Conclusion:Clinical symptoms, inflammatory indicators and chest CT features were significantly different between severe/critical COVID-19 and light/ordinary COVID-19 patients, and it is helpful for early identification of severe/critical COVID-19 and assessment of its prognosis when combined with age, PII and CRP.
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