Abstract: Objective:To summarize the characteristics of COVID-19 ground glass opacity(GGO) on HRCT, and to explore its anatomical and pathological basis.Methods:The HRCT imagings of 87 cases with COVID-19 were analyzed retrospectively and the characteristics of GGO were summed up. Results:A total of 255 GGO lesions were found, and their distribution characteristics were as follows:4 in the central region(1.57%), 120 in the peripheral region(47.06%), and 131 in the subpleural region(51.37%). The structural features of the lesions:48 lesions with paving stone signs(18.82%), and 191 lesions with small thickened blood vessels.The marginal features:96 lesions with arcuate indentations(37.65%) and 75 lesions with pleural traction signs(29.41%). Conclusion:The peripheral distribution of GGO is the typical HRCT manifestation of COVID-19, and paving stone sign, arcuate indentation sign and pleural traction sign are the manifestations of the lesion organization and fibrosis.