Abstract: Objective: To analysis of multi-slice CT imaging features of 43 cases of endobronchial tuberculosis (EBTB) patients, and to improve the ability of recognition and differential diagnosis of EBTB. Methods: A retrospective analysis of the clinical manifestations of 43 cases by fiberoptic bronchoscopy and surgical pathology confirmed EBTB patients, CT data and follow-up results, summarized its multislice spiral CT features. Results: CT is shown as of EBTB: (1) Lesions involving a wide range of multi-branching bronchial simultaneously involved, common in the upper lobe bronchus. (2) Bronchial wall showed more irregular thickening, luminal showed varying degrees of stenosis, a few tracheas can complete occlusion, leading to atelectasis. (3) Some calcification of the bronchial wall were observed. (4) There were some intrathomcal tuberous foci frequently. (5) Lymph node enlargement and calcification. Conclusion: Multislice spiral CT scan more clearly observe the bronchial lesions, it provides an important reference value for the diagnosis and differential diagnosis of EBTB, improve the diagnostic rate of EBTB.