Abstract: At present, imaging diagnosis of the pancreas is gradually changed from the single morphological diagnosis to combining of morphological and functional diagnosis in the CT perfusion; CT perfusion is a kind of functional imaging technology developed on the basis of conventional CT scan, which could earlier detect and diagnose the pancreatic diseases by observing the pancreas microcirculation changes using CT perfusion. It is a hotspot in the research field of the pancreas disease. Radiation dose was significantly increased using CT perfusion scanning with conventional scanning conditions. How to do low dose CT perfusion becomes the key direction of current discussion. This review deals with the application status and research trends of the technology in the low-dose CT perfusion imaging of pancreas.