Abstract: Objective: To evaluate the value of 64-MSCT diagnosis of intestinal tumor. Methods: The imaging data of 39 patients with intestinal cancer were retrospectively analyzed in our hospital from july 2013 to may 2016, All the patients were examined with water imaging technique. Coronal plane and Sagittal plane imaging reconstruction was performed by work station multiplanar reconstruction(MPR), and sectional plane imaging was combined. CT findings of 39 patients of intestinal tumor were retrospectively analyzed. Results: In 39 cases of intestinal tumor.2 cases of small intestinal adenocarcinoma.1 case of malignant lymphoma. 2 cases of gastrointestinal stromal tumors. 3 cases of ileocecal junction tumor. 22 cases of hemicolon tumor. 9 cases of rectal tumor. Tumor complicated with intestinal obstruction in 2 cases, combined intussusception in 1 case, tumor perforation in 1 case. Tumor invasion and 28 cases of deep muscularis, break through the infringement of 16 cases of fat around the gap size film layer, around 10 cases of lymph node metastasis, liver metastasis in 1 case.Conculsion:64 layer spiral CT on gastrointestinal tumor detection rate is high, can accurately determine the patient's pathological changes, and help the tumor qualitative, has diagnostic value in intestinal tumor.