Abstract: Objective: Comparison of CT coronary artery imaging(CTCA) and PET-CT myocardial perfusion imaging(MPI) for relevant coronary artery stenos is and pinpoints the value of the "criminal" blood vessels. Methods: A retrospective analysis of the Affiliated hospital of Inner Mongolia Medical University from March 2009 to December 2014,the clinical diagnosis and 59 patients with suspected CAD were used CTCA and MPI within four weeks. By two experienced imaging and nuclear medicine physician images and data analysis, according to the segmental coronary artery blood flow characteristics, analysis of coronary artery blood supply region and sarcomere corresponding relation we used the Spearman rank correlation and Pearson and Kappa test method. Results: According to the LAD, LCX, RCA three coronary artery myocardial part of dominion on 59 patients, total 177 vessels and coronary vascular level 0, 58 branch; 24 Ⅰ level; 33 the Ⅱ level; 40 Ⅲ level; 22 Ⅳ level. Perfusion 0, 63; 1 minute 30; 2 minutes and 45; 3 minutes and 27 teams; 4 points, 12.Three CTCA coronary arteries with MPI line of correlation analysis and alignment analysis respectively, both for the positive correlation, self-agreement is higher. LAD r = 0.764, P = 0.000; LCX r = 0.593, P = 0.000; RCA r = 0.831, P = 0.000. LAD k = 0.666, P = 0.000; LCX k = 0.601, P = 0.000; RCA k = 0.559, P = 0.000. Conclusion: CTCA anatomic information and MPI physiological functional combination, effective complementary, able to pinpoint a combination of CAD patients "criminals" blood vessels, greatly improve the CAD diagnosis accuracy, and provide powerful basis for clinical treatment and prognosis judgment.